When my Grandma Francine died at 72 of cardiovascular disease (CVD), I was devastated. Like a second mom to me, she was one of my closest confidants, my comfort, and I loved her (and still do) like crazy. My husband and I had just gotten married, and we were still processing the loss of his grandfather, who had died of liver cancer the month before. Bedridden and unable to attend my wedding, her health had been failing for a few years. Several strokes had stripped her of a job she enjoyed, and the ability to drive a car. The last time she drove a vehicle, she suffered a mini-stroke and ended up parked in front of a random strip mall. The only thing she could remember was the sound of horns honking and cars coming toward her. By the grace of God, nobody was injured. Eventually, she was rendered speechless and robbed her of a most prized possession, her mind. So much so, she didn’t even realize she was playing in her own excrement when my aunt was driving her home from a doctor’s visit. It’s like the old saying, “Once an adult, and twice a child.”
Her father had also died young but from a massive heart attack. He was 59 years old, a mere 13 years older than I am now. My grandmother was heartbroken and sad for many, many years after his death. So what is the take away from all this? Heart disease runs in my family and takes away people who are dearly loved, far too early. Furthermore, it begs the question, since my grandma and great-grandpa died from cardiovascular disease, does that mean my children and grandchildren will lose me the same way?
“Your Bad Habits Are As Inherited As Your Bad Genes.”
The other day I was listening to Dr. Neal Barnard, MD, on a podcast. A very articulate and tremendously intelligent man, Dr. Barnard is a trailblazer in preventive medicine, good nutrition, and higher ethical standards in research. In the segment, Rich Roll (one of the best interviewers ever) and Dr. Barnard were talking about something called epigenetics. Here is a quick analogy that might help understand epigenetics. “Think of the human life span as a very long movie. The cells would be the actors and actresses, basic units that make up the movie. DNA, in turn, would be the script —the DNA sequence would be the words of the script, and certain blocks of these words that instruct key actions or events to take place would be the genes. (1)
We all have two types of genes. Some genes are “Dictator” genes. “You, Stephanie, will have blonde hair and blue eyes.” These genes give you orders, and you can’t argue with them. But then there are the other guys, the “Committee” genes. They make suggestions, and if you don’t like them, you can refuse. “Hey, Steph, how about some clogged arteries?” Nah, I think I’ll pass. Certain circumstances in life can cause genes to either be “silenced” or “expressed” over time. They can be turned off (becoming dormant) or turned on (becoming active). What you eat, where you live, who you interact with, when you sleep, how you exercise, even aging – all of these can eventually cause chemical modifications around the genes that will turn those genes on or off over time. (2)
Still with me?
So this made me wonder if there was a relationship between epigenetics and cardiovascular disease. Is CVD a familial death sentence? In his book “How Not To Die,” Dr. Michael Greger explains, “For most of our leading killers (heart disease being number one), non-genetic factors like diet can account for 80-90% of cases.” Migration studies and twin studies show us this is not just a case of bad genes. When a person moves from a place where there is a high incidence of heart disease to a place where heart disease is virtually non-existent, their disease rates decrease.
Conversely, when a person moves from a place where there is a low incidence of disease, their risk rises when they move to a place where there are higher incidents of illness. In a twin study funded by the American Heart Association, 500 twin pairs were examined for CVD. Some were non-identical (only share 50% of the same genes), and some were identical twins (they share the same genes). The results of the identical twins showed that one twin could die early of a heart attack, and the other can live a long, healthy life with clean arteries depending on what they ate and how they lived.”
Even if I have a genetic predisposition to heart disease, it doesn’t mean that I have to die from it.
“Your genes are the gun, but it’s your lifestyle that pulls the trigger.”
Bad habits also run in families. Families that grow up together and eat together end up “inheriting” bad eating habits from mom and dad. That explains why entire families are obese; suffer from CVD, diabetes, and other chronic diseases. Overeating, consuming foods high in fat and cholesterol, eating fast food for breakfast and dinner, and a sedentary lifestyle are all significant factors that lead to early death from Cardiovascular Disease.
Worse, the more behavioral risk factors people have—smoking and eating a high-fat diet and not exercising, for instance—the less likely they are to be interested in information about living healthier. (3)
So what do we do about it?
Without question, diet is the most critical component of preventing, halting, and in many cases, even reversing the effects of cardiovascular disease. A high fiber diet mostly whole, plant-based foods were scientifically proven to lower cholesterol and dissolve plaque build-up in the arteries without medications or surgery. In fact, diet is so powerful that Dr. Barnard equates eating a plant-based diet as the nutritional equivalent to quitting smoking. So does this mean a vegan or vegetarian diet? According to Dr. Joel Fuhrman, MD, striving to eat at least 90% of your calories from the unrefined plant foods, you construct a health-promoting, disease-preventing diet. But what about the remaining 10%? While I love the idea of every person eating a 100% whole food plant-based diet, I know it’s not a realistic option for everyone.
In a large scale study of the oldest living people globally, National Geographic researcher Dan Buettner examined five places in the world – dubbed “Blue Zones” – areas where people live the longest and are healthiest. The data showed the need to LIMIT MEAT. “Think of meat as a celebratory food,” Buettner said. “Portions should be no larger than a deck of cards, once or twice a week. Avoid processed meats such as hot dogs, bacon, and sausages.” FISH IS FINE. Enjoy fish up to three times weekly. Wild-caught salmon or smaller fish like sardines, trout, snapper, cod, and anchovies are okay choices. Limit portion sizes to 3 ounces (about the size of the palm of your hand.)” You need to know other severe issues with fish, such as sustainability and the health dangers of mercury consumption.
Quick Side Note: Epigenetics and Cancer.
Dr. Dean Ornish and his colleagues took biopsies from men with prostate cancer before and after three months of intensive lifestyle changes, including a diet rich in whole plant-based foods. Without any chemo or radiation, a positive change was noted in 500 different genes! The expression of disease-preventing genes was boosted, and those that promoted the cancer were suppressed. (4)
Performing a variety of yoga postures, stretches, and exercises muscles. This helps them become more sensitive to insulin, which is essential for controlling blood sugar. Deep breathing can help lower blood pressure. Mind-calming meditation, another crucial part of yoga, quiets the nervous system, and eases stress. All of these improvements may help prevent heart disease and can help people with cardiovascular problems. (5)
It can be as simple as taking a walk. While walking 60 minutes per week can reduce your overall mortality by 3%, walking 300 minutes a week, or 40 minutes a day, can reduce your mortality rate by 14%! So, in this case, more really is better. And physical activity doesn’t mean just going to the gym. It can mean anything from cycling and playing Frisbee to practicing yoga.
In a 2007 study that followed more than 6,000 men and women aged 25 to 74 for 20 years, researchers found that emotional vitality—a sense of enthusiasm, of hopefulness, of engagement in life, and the ability to face life’s stresses with emotional balance—appears to reduce the risk of coronary heart disease. The protective effect was distinct and measurable, even when considering such wholesome behaviors as not smoking and regular exercise. Optimism cuts the risk of coronary heart disease by half. (6)
**It has also been shown that being good at “self-regulation,” i.e., bouncing back from stressful challenges and knowing that things will eventually look up again, and choosing healthy behaviors can be a significant factor in reducing heart disease. The idea is that you are avoiding risky behaviors such as drinking alcohol to excess and regular overeating.
How do I begin to make a change to a plant-based diet? What behaviors do I need to improve to stick with it? I am starting from scratch, and enjoy sugars, carbohydrates, and meats. It will be a significant life change for me, but I have arthritis, high blood pressure, and high cholesterol (the latter two conditions are controlled with medications). Arthritis in my hands is painful, and anti-inflammatory drugs are not helping.
Think evolution rather than revolution. Introduce one new, plant-based recipe per month, and in a year, you have great ideas for eating for two weeks. Identify one or two types of breakfast you can eat on most days. I recommend a smoothie. It’s a great way to get at least 3-4 servings of fruits and vegetables in one meal. Replace all of the simple carbohydrates, bread, and pasta with 100 percent whole-grain product. Add beans to your salads and eat more vegetables.
Any change requires some effort. If you want a different result, i.e., Better health, you have to be willing to introduce changes that may be uncomfortable at first. Our taste buds do not like change. So, essentially you have to educate your taste buds and do this with mindfulness and a sense of purpose when you are changing your diet. If you stay long enough, one month, or two off of addictive sugars and fats (and salt as well), you will stop craving those altogether. Just take the first step in your mind that you want to change to a plant-based diet if you feel that such changes will benefit you.